Recent Advances in Hematopoietic Stem Cell Gene Therapy
نویسنده
چکیده
Hematopoietic stem cell transplantation (HSCT) has a half-century history. It is currently an indispensable treatment for not only incurable blood diseases such as aplastic anemia and severe hemolytic anemia, but also malignant hematological diseases such as leukemia and lymphoma. Although allergenic HSCT is also used to treat hereditary diseases, its indica‐ tions are restricted because of critical complications including regimen-related toxicities in‐ volving conditioning, infection, and graft-versus-host disease.
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